![]() Barotrauma was also associated with a significant increased in the ICU length of stay and mortality.īarotrauma is a feared complication of mechanical ventilation and is associated with increased morbidity and mortality. In a cohort of patients in whom airway pressures and tidal volume are limited, barotrauma is more likely in patients ventilated due to underlying lung disease (acute or chronic). Case-control analysis showed increased mortality in patients with barotrauma (51.4 vs 39.2% p=0.04) and prolonged ICU stay. Logistic regression analysis identified as factors independently associated with barotrauma: asthma, ILD ARDS as primary reason for mechanical ventilation and ARDS as a complication during the course of mechanical ventilation. Patients with and without barotrauma did not differ in any ventilator parameter. The incidence varied according to the reason for mechanical ventilation: 2.9% of patients with chronic obstructive pulmonary disease 6.3% of patients with asthma 10.0% of patients with chronic interstitial lung disease (ILD) 6.5% of patients with acute respiratory distress syndrome (ARDS) and 4.2% of patients with pneumonia. Barotrauma was present in 154 patients (2.9%). Measurements and resultsīaseline demographic data, primary indication for mechanical ventilation, daily ventilator settings, multiple-organ failure over the course of mechanical ventilation and outcome were collected. ![]() Patients and participantsĪ total of 5183 patients mechanically ventilated for more than 12 h. ![]() Prospective cohort of 361 intensive care units from 20 countries. To determine the incidence, risk factors, and outcome of barotrauma in a cohort of mechanically ventilated patients where limited tidal volumes and airway pressures were used. ![]()
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